Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent.
SF 86-327 is a new antimycotic agent of the allylamine type. Its primary action appears to be the inhibition of ergosterol biosynthesis at the point of squalene epoxidation, as was previously found with the related compound naftifine. Biosynthesis was measured by incorporation of [14C]acetate into s...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1985
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4039119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.2.252 |
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