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Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.

We report the ultrastructural alterations induced during the proliferative stages of Trypanosoma (Schizotrypanum) cruzi, the causative agent of Chagas' disease, by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, which had previously been shown to be potent growth inhibitors who...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Lazardi, K, Urbina, J A, de Souza, W
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2073100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.11.2097
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