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Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.

We report the ultrastructural alterations induced during the proliferative stages of Trypanosoma (Schizotrypanum) cruzi, the causative agent of Chagas' disease, by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, which had previously been shown to be potent growth inhibitors who...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Lazardi, K, Urbina, J A, de Souza, W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2073100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.11.2097
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