Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase

Poly(ADP-ribose) polymerase (PARP) is implicated in the maintenance of genomic integrity, given that inhibition or depletion of this enzyme increases genomic instability in cells exposed to genotoxic agents. We previously showed that immortalized fibroblasts derived from PARP(−/−) mice exhibit an un...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Simbulan-Rosenthal, Cynthia M., Ly, Danith H., Rosenthal, Dean S., Konopka, Genevieve, Luo, RuiBai, Wang, Zhao-Qi, Schultz, Peter G., Smulson, Mark E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2000
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC17190/
https://ncbi.nlm.nih.gov/pubmed/11016956
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