Detection of DNA breaks in apoptotic cells utilizing the DNA binding domain of poly(ADP-ribose) polymerase with fluorescence microscopy.

The DNA binding domain (DBD) of poly(ADP-ribose) polymerase (PARP) has proved to be a novel, highly sensitive probe for detecting DNA breaks in intact cells undergoing apoptosis. A recombinant peptide spanning the DNA binding domain of PARP was expressed, purified and used to detect DNA strand break...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Rosenthal, D S, Ding, R, Simbulan-Rosenthal, C M, Cherney, B, Vanek, P, Smulson, M
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC146589/
https://ncbi.nlm.nih.gov/pubmed/9060441
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki