Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase
Poly(ADP-ribose) polymerase (PARP) is implicated in the maintenance of genomic integrity, given that inhibition or depletion of this enzyme increases genomic instability in cells exposed to genotoxic agents. We previously showed that immortalized fibroblasts derived from PARP(−/−) mice exhibit an un...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11016956/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.200285797 |
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