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A Thiol-Reactive (18)F-Labeling Agent, N-[2-(4-(18)F-Fluorobenzamido)Ethyl]Maleimide, and Synthesis of RGD Peptide-Based Tracer for PET Imaging of α(v)β(3) Integrin Expression
The cell adhesion molecule integrin α(v)β(3) plays a key role in tumor angiogenesis and metastasis. A series of (18)F-labeled RGD peptides have been developed for PET of integrin expression based on primary amine-reactive prosthetic groups. In this study we introduced a new method of labeling RGD pe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1704081/ https://ncbi.nlm.nih.gov/pubmed/16818952 |
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