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microPET of Tumor Integrin α(v)β(3) Expression Using (18)F-Labeled PEGylated Tetrameric RGD Peptide ((18)F-FPRGD4)

In vivo imaging of α(v)β(3) expression has important diagnostic and therapeutic applications. Multimeric cyclic RGD peptides are capable of improving the integrin α(v)β(3)–binding affinity due to the polyvalency effect. Here we report an example of (18)F-labeled tetrameric RGD peptide for PET of α(v...

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Detalhes bibliográficos
Main Authors: Wu, Zhanhong, Li, Zi-Bo, Chen, Kai, Cai, Weibo, He, Lina, Chin, Frederick T., Li, Fang, Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183663/
https://ncbi.nlm.nih.gov/pubmed/17704249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.107.040816
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