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Click Chemistry for (18)F-Labeling of RGD Peptides and microPET Imaging of Tumor Integrin α(v)β(3) Expression
The cell adhesion molecule integrin α(v)β(3) plays a key role in tumor angiogenesis and metastasis. A series of (18)F-labeled RGD peptides have been developed for PET of integrin expression based on primary amine reactive prosthetic groups. In this study, we report the use of the Cu(I)-catalyzed Hui...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183694/ https://ncbi.nlm.nih.gov/pubmed/18030991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700226v |
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