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Click Chemistry for (18)F-Labeling of RGD Peptides and microPET Imaging of Tumor Integrin α(v)β(3) Expression

The cell adhesion molecule integrin α(v)β(3) plays a key role in tumor angiogenesis and metastasis. A series of (18)F-labeled RGD peptides have been developed for PET of integrin expression based on primary amine reactive prosthetic groups. In this study, we report the use of the Cu(I)-catalyzed Hui...

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Detalhes bibliográficos
Main Authors: Li, Zi-Bo, Wu, Zhanhong, Chen, Kai, Chin, Frederick T., Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183694/
https://ncbi.nlm.nih.gov/pubmed/18030991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700226v
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