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3-(18)F-Fluoropropane-1-thiol and (18)F-PEG(4)-1-thiol: versatile prosthetic groups for radiolabeling maleimide functionalized peptides

The efficient radiosynthesis of biomolecules utilizing minute quantities of maleimide substrate is important for availability of novel peptide molecular imaging agents. We evaluated both 3-(18)F-fluoropropane-1-thiol and 2-(2-(2-(2-(18)F-fluoroethoxy)ethoxy)ethoxy)ethane-1-thiol ((18)F-fluoro-PEG(4)...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Jacobson, Orit, Wang, Zhantong, Yu, Guocan, Ma, Ying, Chen, Xiaoyuan, Kiesewetter, Dale O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983705/
https://ncbi.nlm.nih.gov/pubmed/31402203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.08.002
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