3-(18)F-Fluoropropane-1-thiol and (18)F-PEG(4)-1-thiol: versatile prosthetic groups for radiolabeling maleimide functionalized peptides

The efficient radiosynthesis of biomolecules utilizing minute quantities of maleimide substrate is important for availability of novel peptide molecular imaging agents. We evaluated both 3-(18)F-fluoropropane-1-thiol and 2-(2-(2-(2-(18)F-fluoroethoxy)ethoxy)ethoxy)ethane-1-thiol ((18)F-fluoro-PEG(4)...

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Udgivet i:Bioorg Med Chem
Main Authors: Jacobson, Orit, Wang, Zhantong, Yu, Guocan, Ma, Ying, Chen, Xiaoyuan, Kiesewetter, Dale O.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983705/
https://ncbi.nlm.nih.gov/pubmed/31402203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.08.002
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