A Thiol-Reactive (18)F-Labeling Agent, N-[2-(4-(18)F-Fluorobenzamido)Ethyl]Maleimide, and Synthesis of RGD Peptide-Based Tracer for PET Imaging of α(v)β(3) Integrin Expression

The cell adhesion molecule integrin α(v)β(3) plays a key role in tumor angiogenesis and metastasis. A series of (18)F-labeled RGD peptides have been developed for PET of integrin expression based on primary amine-reactive prosthetic groups. In this study we introduced a new method of labeling RGD pe...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cai, Weibo, Zhang, Xianzhong, Wu, Yun, Chen, Xiaoyuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1704081/
https://ncbi.nlm.nih.gov/pubmed/16818952
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