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The effect of bretylium on intracellular cardiac action potentials in relation to its anti-arrhythmic and local anaesthetic activity

1. The initial effect of bretylium tosylate on isolated rabbit atria was to increase conduction velocity, contraction heights, spontaneous frequency and maximum driven frequency, and to reduce electrical threshold. At concentrations of 200 mg/l. or less, these were the only effects, and were consist...

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Autors principals: Papp, J. Gy., Williams, E. M. Vaughan
Format: Artigo
Idioma:Inglês
Publicat: 1969
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1703703/
https://ncbi.nlm.nih.gov/pubmed/5348427
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