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A comparison of the anti-arrhythmic actions of I.C.I. 50172 and (—)-propranolol and their effects on intracellular cardiac action potentials and other features of cardiac function
1. I.C.I. 50172 had marked quinidine-like effects on intracellular cardiac action potentials at concentrations above 20 mg/l. (6·61 × 10(-5)M). The rate of rise and overshoot of the action potential, conduction velocity and contractions were decreased. (—)-Propranolol had similar effects at less tha...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1969
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1703656/ https://ncbi.nlm.nih.gov/pubmed/4390670 |
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