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A comparison of the anti-arrhythmic actions of I.C.I. 50172 and (—)-propranolol and their effects on intracellular cardiac action potentials and other features of cardiac function

1. I.C.I. 50172 had marked quinidine-like effects on intracellular cardiac action potentials at concentrations above 20 mg/l. (6·61 × 10(-5)M). The rate of rise and overshoot of the action potential, conduction velocity and contractions were decreased. (—)-Propranolol had similar effects at less tha...

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Detalhes bibliográficos
Main Authors: Papp, J. Gy., Williams, E. M. Vaughan
Formato: Artigo
Idioma:Inglês
Publicado em: 1969
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1703656/
https://ncbi.nlm.nih.gov/pubmed/4390670
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