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A third class of anti-arrhythmic action: Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscle, of MJ 1999 and AH 3474

1. Both MJ 1999 and AH 3474 protected guinea-pigs anaesthetized with urethane against ouabain-induced ventricular fibrillation. 2. MJ 1999 had 1/90, and AH 3474 1/30, of the activity of procaine in reducing the height of the action potential of frog sciatic nerve. 3. MJ 1999 and AH 3474 reduced the...

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Detalhes bibliográficos
Main Authors: Singh, B. N., Williams, E. M. Vaughan
Formato: Artigo
Idioma:Inglês
Publicado em: 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702723/
https://ncbi.nlm.nih.gov/pubmed/5485144
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