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The role of intracellular sodium activity in the anti-arrhythmic action of local anaesthetics in sheep Purkinje fibres.

The effects of lidocaine have been examined on the arrhythmogenic transient inward current (ITI) in voltage-clamped sheep cardiac Purkinje fibres. Tension and intracellular Na activity (aiNa) were measured simultaneously. The addition of lidocaine (200-300 microM) produced an immediate decrease of i...

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Bibliografiska uppgifter
Huvudupphovsmän: Eisner, D A, Lederer, W J, Sheu, S S
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1983
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199208/
https://ncbi.nlm.nih.gov/pubmed/6310096
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