טוען...
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-αBcrystallin) complex
Growth factor-dependent accumulation of the cyclin D1 proto-oncogene is balanced by its rapid phosphorylation-dependent proteolysis. Degradation is triggered by threonine 286 phosphorylation, which promotes its ubiquitination by an unknown E3 ligase. We demonstrate that Thr286 phosphorylated cyclin...
שמור ב:
| Main Authors: | , , , , , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2006
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1702390/ https://ncbi.nlm.nih.gov/pubmed/17081987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.09.007 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|