Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators

DNA sequencing by synthesis (SBS) on a solid surface during polymerase reaction offers a paradigm to decipher DNA sequences. We report here the construction of such a DNA sequencing system using molecular engineering approaches. In this approach, four nucleotides (A, C, G, T) are modified as reversi...

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Detalhes bibliográficos
Main Authors: Ju, Jingyue, Kim, Dae Hyun, Bi, Lanrong, Meng, Qinglin, Bai, Xiaopeng, Li, Zengmin, Li, Xiaoxu, Marma, Mong Sano, Shi, Shundi, Wu, Jian, Edwards, John R., Romu, Aireen, Turro, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702316/
https://ncbi.nlm.nih.gov/pubmed/17170132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609513103
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