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Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
DNA sequencing by synthesis (SBS) on a solid surface during polymerase reaction offers a paradigm to decipher DNA sequences. We report here the construction of such a DNA sequencing system using molecular engineering approaches. In this approach, four nucleotides (A, C, G, T) are modified as reversi...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1702316/ https://ncbi.nlm.nih.gov/pubmed/17170132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609513103 |
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