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Design and synthesis of a 3′-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis

DNA sequencing by synthesis (SBS) offers an approach for potential high-throughput sequencing applications. In this method, the ability of an incoming nucleotide to act as a reversible terminator for a DNA polymerase reaction is an important requirement to unambiguously determine the identity of the...

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מידע ביבליוגרפי
Main Authors: Ruparel, Hameer, Bi, Lanrong, Li, Zengmin, Bai, Xiaopeng, Kim, Dae Hyun, Turro, Nicholas J., Ju, Jingyue
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087948/
https://ncbi.nlm.nih.gov/pubmed/15829589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501962102
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