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A photocleavable fluorescent nucleotide for DNA sequencing and analysis
DNA sequencing by synthesis during a polymerase reaction using laser-induced fluorescence detection is an approach that has a great potential to increase the throughput and data quality of DNA sequencing. We report the design and synthesis of a photocleavable fluorescent nucleoside triphosphate, one...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141009/ https://ncbi.nlm.nih.gov/pubmed/12515853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242729199 |
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