An important role for RUNX3 in human L1 transcription and retrotransposition
LINE-1s (long interspersed nuclear elements-1) are abundant non-LTR retrotransposons that comprise 17% of the human genome. The 5′ untranslated region (5′UTR) of human L1 (L1Hs) houses a poorly understood internal promoter. Here we report that mutations at a putative runt-domain transcription factor...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg663 |
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