An important role for RUNX3 in human L1 transcription and retrotransposition

LINE-1s (long interspersed nuclear elements-1) are abundant non-LTR retrotransposons that comprise 17% of the human genome. The 5′ untranslated region (5′UTR) of human L1 (L1Hs) houses a poorly understood internal promoter. Here we report that mutations at a putative runt-domain transcription factor...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Yang, Nuo, Zhang, Lin, Zhang, Yue, Kazazian Jr, Haig H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg663
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