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Precise mapping of an IGF-I-binding site on the IGF-1R
The IGF-1R [type 1 IGF (insulin-like growth factor) receptor] is activated upon binding to IGF-I and IGF-II leading to cell growth, survival and migration of both normal and cancerous cells. We have characterized the binding interaction between the IGF-1R and its ligands using two high-affinity mous...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Portland Press Ltd.
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698672/ https://ncbi.nlm.nih.gov/pubmed/16981855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060890 |
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