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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay
The activity and levels of the metazoan HIF (hypoxia-inducible factor) are regulated by its hydroxylation, catalysed by 2OG (2-oxoglutarate)- and Fe(II)-dependent dioxygenases. An oxygen consumption assay was developed and used to study the relationship between HIF hydroxylase activity and oxygen co...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698668/ https://ncbi.nlm.nih.gov/pubmed/16952279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061151 |
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