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Timing and Sequence Requirements Defined for Embryonic Maintenance of Imprinted DNA Methylation at Rasgrf1

Epigenetic programming is critical for normal development of mammalian embryos. Errors cause misexpression of genes and aberrant development (E. Li, C. Beard, and R. Jaenisch, Nature 366:362-365, 1993). Imprinted genes are important targets of epigenetic regulation, but little is known about how the...

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Bibliografiske detaljer
Main Authors: Holmes, Rebecca, Chang, Yanjie, Soloway, Paul D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698547/
https://ncbi.nlm.nih.gov/pubmed/17030618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00058-06
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