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Regulation of DNA methylation of Rasgrf1

In mammals, DNA is methylated at cytosines within CpG dinucleotides. Properly regulated methylation is crucial for normal development1,2. Inappropriate methylation may contribute to tumorigenesis by silencing tumor-suppressor genes3-10 or by activating growth-stimulating genes11-13. Although many ge...

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Autori principali: Yoon, Bong June, Herman, Herry, Sikora, Aimee, Smith, Laura T., Plass, Christoph, Soloway, Paul D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756564/
https://ncbi.nlm.nih.gov/pubmed/11753386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng795
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