Regulation of DNA methylation of Rasgrf1

In mammals, DNA is methylated at cytosines within CpG dinucleotides. Properly regulated methylation is crucial for normal development1,2. Inappropriate methylation may contribute to tumorigenesis by silencing tumor-suppressor genes3-10 or by activating growth-stimulating genes11-13. Although many ge...

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Bibliographic Details
Main Authors: Yoon, Bong June, Herman, Herry, Sikora, Aimee, Smith, Laura T., Plass, Christoph, Soloway, Paul D.
Format: Artigo
Language:Inglês
Published: 2001
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756564/
https://ncbi.nlm.nih.gov/pubmed/11753386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng795
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