Rasgrf1 Imprinting Is Regulated by a CTCF-Dependent Methylation-Sensitive Enhancer Blocker

Imprinted methylation of the paternal Rasgrf1 allele in mice occurs at a differentially methylated domain (DMD) 30 kbp 5′ of the promoter. A repeated sequence 3′ of the DMD regulates imprinted methylation, which is required for imprinted expression. Here we identify the mechanism by which methylatio...

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Detalhes bibliográficos
Main Authors: Yoon, Bongjune, Herman, Herry, Hu, Benjamin, Park, Yoon Jung, Lindroth, Anders, Bell, Adam, West, Adam G., Chang, Yanjie, Stablewski, Aimee, Piel, Jessica C., Loukinov, Dmitri I., Lobanenkov, Victor V., Soloway, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316951/
https://ncbi.nlm.nih.gov/pubmed/16314537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.11184-11190.2005
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