Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

Genomic imprinting causes parental origin–specific monoallelic gene expression through differential DNA methylation established in the parental germ line. However, the mechanisms underlying how specific sequences are selectively methylated are not fully understood. We have found that the components...

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Detalhes bibliográficos
Main Authors: Watanabe, Toshiaki, Tomizawa, Shin-ichi, Mitsuya, Kohzoh, Totoki, Yasushi, Yamamoto, Yasuhiro, Kuramochi-Miyagawa, Satomi, Iida, Naoko, Hoki, Yuko, Murphy, Patrick J., Toyoda, Atsushi, Gotoh, Kengo, Hiura, Hitoshi, Arima, Takahiro, Fujiyama, Asao, Sado, Takashi, Shibata, Tatsuhiro, Nakano, Toru, Lin, Haifan, Ichiyanagi, Kenji, Soloway, Paul D., Sasaki, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368507/
https://ncbi.nlm.nih.gov/pubmed/21566194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1203919
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