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Contour Length and Refolding Rate of a Small Protein Controlled by Engineered Disulfide Bonds
The introduction of disulfide bonds into proteins creates additional mechanical barriers and limits the unfolded contour length (i.e., the maximal extension) measured by single-molecule force spectroscopy. Here, we engineer single disulfide bonds into four different locations of the human cardiac ti...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1697845/ https://ncbi.nlm.nih.gov/pubmed/17028145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.091561 |
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