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Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques
The mechanism by which mechanical force regulates the kinetics of a chemical reaction is unknown. Here, we use single-molecule force–clamp spectroscopy and protein engineering to study the effect of force on the kinetics of thiol/disulfide exchange. Reduction of disulfide bonds through the thiol/dis...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464324/ https://ncbi.nlm.nih.gov/pubmed/16645035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511035103 |
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