NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

NF-κB downregulates tumor necrosis factor (TNF)-induced c-Jun N-terminal kinase (JNK) activation that promotes cell death, but the mechanism is not yet fully understood. By using murine embryonic fibroblasts (MEFs) that are deficient in TNF receptor-associated factor (TRAF) 2 and TRAF5 (DKO) or p65...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Sakon, Sachiko, Xue, Xin, Takekawa, Mutsuhiro, Sasazuki, Tomonari, Okazaki, Tatsuma, Kojima, Yuko, Piao, Jian-Hu, Yagita, Hideo, Okumura, Ko, Doi, Takahiro, Nakano, Hiroyasu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2003
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC169052/
https://ncbi.nlm.nih.gov/pubmed/12881424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg379
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller