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An antiapoptotic protein, c-FLIP(L), directly binds to MKK7 and inhibits the JNK pathway
Inhibition of NF-κB activation increases susceptibility to tumor necrosis factor (TNF)α-induced cell death, concurrent with caspases and prolonged c-Jun N-terminal kinase (JNK) activation, and reactive oxygen species (ROS) accumulation. However, the detailed mechanisms are unclear. Here we show that...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1679768/ https://ncbi.nlm.nih.gov/pubmed/17110930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601423 |
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