Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly

Inter-helix hydrogen bonding involving asparagine (Asn, N), glutamine (Gln, Q), aspartic acid (Asp, D) or glutamic acid (Glu, E) can drive efficient di- or trimerization of transmembrane helices in detergent micelles and lipid bilayers. Likewise, Asn–Asn and Asp–Asp pairs can promote the formation o...

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Bibliographic Details
Main Authors: Meindl-Beinker, Nadja M, Lundin, Carolina, Nilsson, IngMarie, White, Stephen H, von Heijne, Gunnar
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Scientific Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679787/
https://ncbi.nlm.nih.gov/pubmed/17008929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400818
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