Unique actinomycin D binding to self-complementary d(CXYGGCCY′X′G) sequences: duplex disruption and binding to a nominally base-paired hairpin
Actinomycin D (ACTD) has been shown to bind weakly to the sequence -GGCC-, despite the presence of a GpC site. It was subsequently found, however, that d(CATGGCCATG) binds relatively well to ACTD but exhibits unusually slow association kinetics, contrary to the strong-binding -XGCY- sites. In an eff...
שמור ב:
| הוצא לאור ב: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2003
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg477 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|