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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus mouse hepatitis virus strain A59 is posttranslationally cleaved into an S1 receptor binding unit and an S2 membrane fusion unit. The latter is thought to contain an internal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bosch, Berend Jan, van der Zee, Ruurd, de Haan, Cornelis A. M., Rottier, Peter J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC167208/
https://ncbi.nlm.nih.gov/pubmed/12885899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8801-8811.2003
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