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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus mouse hepatitis virus strain A59 is posttranslationally cleaved into an S1 receptor binding unit and an S2 membrane fusion unit. The latter is thought to contain an internal...

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Detalhes bibliográficos
Main Authors: Bosch, Berend Jan, van der Zee, Ruurd, de Haan, Cornelis A. M., Rottier, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC167208/
https://ncbi.nlm.nih.gov/pubmed/12885899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8801-8811.2003
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