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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus mouse hepatitis virus strain A59 is posttranslationally cleaved into an S1 receptor binding unit and an S2 membrane fusion unit. The latter is thought to contain an internal...

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Détails bibliographiques
Auteurs principaux: Bosch, Berend Jan, van der Zee, Ruurd, de Haan, Cornelis A. M., Rottier, Peter J. M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC167208/
https://ncbi.nlm.nih.gov/pubmed/12885899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8801-8811.2003
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