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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus mouse hepatitis virus strain A59 is posttranslationally cleaved into an S1 receptor binding unit and an S2 membrane fusion unit. The latter is thought to contain an internal...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Bosch, Berend Jan, van der Zee, Ruurd, de Haan, Cornelis A. M., Rottier, Peter J. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12885899/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.16.8801-8811.2003
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