‘LeishMan’ topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani

The active site tyrosine residue of all monomeric type IB topoisomerases resides in the C-terminal domain of the enzyme. Leishmania donovani, possesses unusual heterodimeric type IB topoisomerase. The small subunit harbors the catalytic tyrosine within the SKXXY motif. To explore the functional rela...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ganguly, Agneyo, Das, Benu Brata, Sen, Nilkantha, Roy, Amit, Dasgupta, Somdeb Bose, Majumder, Hemanta K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2006
Gaiak:
Nucleic Acid Enzymes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1669778/
https://ncbi.nlm.nih.gov/pubmed/17098934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl829
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