Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I

Emergence of the bi-subunit topoisomerase I in the kinetoplastid family (Trypanosoma and Leishmania) has brought a new twist in topoisomerase research related to evolution, functional conservation and preferential sensitivities to the specific inhibitors of type IB topoisomerase family. In the prese...

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Main Authors: Das, Benu Brata, Sen, Nilkantha, Roy, Amit, Dasgupta, Somdeb Bose, Ganguly, Agneyo, Mohanta, Bikash Chandra, Dinda, Biswanath, Majumder, Hemanta K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373691/
https://ncbi.nlm.nih.gov/pubmed/16488884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj502
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