Cl(−) uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1

GABA is the principal inhibitory neurotransmitter in the mature brain, but during early postnatal development the elevated [Cl(−)](i) in immature neocortical neurones causes GABA(A) receptor activation to be depolarizing. The molecular mechanisms underlying this intracellular Cl(−) accumulation rema...

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Библиографические подробности
Главные авторы: Yamada, Junko, Okabe, Akihito, Toyoda, Hiroki, Kilb, Werner, Luhmann, Heiko J, Fukuda, Atsuo
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2004
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665166/
https://ncbi.nlm.nih.gov/pubmed/15090604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.062471
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