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Cl(−) uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1
GABA is the principal inhibitory neurotransmitter in the mature brain, but during early postnatal development the elevated [Cl(−)](i) in immature neocortical neurones causes GABA(A) receptor activation to be depolarizing. The molecular mechanisms underlying this intracellular Cl(−) accumulation rema...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Blackwell Science Inc
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665166/ https://ncbi.nlm.nih.gov/pubmed/15090604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.062471 |
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