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Mapping the architecture of the ATP-binding site of the K(ATP) channel subunit Kir6.2
ATP-sensitive potassium (K(ATP)) channels comprise Kir6.2 and SUR subunits. The site at which ATP binds to mediate K(ATP) channel inhibition lies on Kir6.2, but the potency of block is enhanced by coexpression with SUR1. To assess the structure of the ATP-binding site on Kir6.2, we used a range of a...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665110/ https://ncbi.nlm.nih.gov/pubmed/15004210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.059105 |
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