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Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-β structure
Abnormal filaments consisting of hyperphosphorylated microtubule-associated protein tau form in the brains of patients with Alzheimer's disease, Down's syndrome, and various dementing tauopathies. In Alzheimer's disease and Down's syndrome, the filaments have two characteristic m...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166433/ https://ncbi.nlm.nih.gov/pubmed/12853572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1530287100 |
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