Chimeric recombinases with designed DNA sequence recognition

Site-specific recombination typically occurs only between DNA sequences that have co-evolved with a natural recombinase enzyme to optimize sequence recognition, catalytic efficiency, and regulation. Here, we show that the sequence recognition and the catalysis functions of a recombinase can be speci...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Akopian, Aram, He, Jiuya, Boocock, Martin R., Stark, W. Marshall
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2003
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12837939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1533177100
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