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Chimeric recombinases with designed DNA sequence recognition

Site-specific recombination typically occurs only between DNA sequences that have co-evolved with a natural recombinase enzyme to optimize sequence recognition, catalytic efficiency, and regulation. Here, we show that the sequence recognition and the catalysis functions of a recombinase can be speci...

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Библиографические подробности
Главные авторы: Akopian, Aram, He, Jiuya, Boocock, Martin R., Stark, W. Marshall
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC166373/
https://ncbi.nlm.nih.gov/pubmed/12837939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533177100
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