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Chimeric recombinases with designed DNA sequence recognition

Site-specific recombination typically occurs only between DNA sequences that have co-evolved with a natural recombinase enzyme to optimize sequence recognition, catalytic efficiency, and regulation. Here, we show that the sequence recognition and the catalysis functions of a recombinase can be speci...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Akopian, Aram, He, Jiuya, Boocock, Martin R., Stark, W. Marshall
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166373/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12837939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1533177100
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