Chimeric recombinases with designed DNA sequence recognition
Site-specific recombination typically occurs only between DNA sequences that have co-evolved with a natural recombinase enzyme to optimize sequence recognition, catalytic efficiency, and regulation. Here, we show that the sequence recognition and the catalysis functions of a recombinase can be speci...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12837939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1533177100 |
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