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Chimeric recombinases with designed DNA sequence recognition
Site-specific recombination typically occurs only between DNA sequences that have co-evolved with a natural recombinase enzyme to optimize sequence recognition, catalytic efficiency, and regulation. Here, we show that the sequence recognition and the catalysis functions of a recombinase can be speci...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166373/ https://ncbi.nlm.nih.gov/pubmed/12837939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533177100 |
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