Unique amino acids cluster for switching from the dehydrogenase to oxidase form of xanthine oxidoreductase
In mammals, xanthine oxidoreductase is synthesized as a dehydrogenase (XDH) but can be readily converted to its oxidase form (XO) either by proteolysis or modification of cysteine residues. The crystal structures of bovine milk XDH and XO demonstrated that atoms in the highly charged active-site loo...
में बचाया:
| में प्रकाशित: | Proc Natl Acad Sci U S A |
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| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2003
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12817083/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1431485100 |
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