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Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR–TAR* and TAR–aptamer
A RNA aptamer (R06) raised against the trans- activation responsive (TAR) element of HIV-1 was previously shown to generate a loop–loop complex whose stability is strongly dependent on the selected G and A residues closing the aptamer loop. The rationally designed TAR* RNA hairpin with a loop sequen...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165981/ https://ncbi.nlm.nih.gov/pubmed/12853646 |
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