Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR–TAR* and TAR–aptamer

A RNA aptamer (R06) raised against the trans- activation responsive (TAR) element of HIV-1 was previously shown to generate a loop–loop complex whose stability is strongly dependent on the selected G and A residues closing the aptamer loop. The rationally designed TAR* RNA hairpin with a loop sequen...

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Bibliografiska uppgifter
Huvudupphovsmän: Beaurain, François, Di Primo, Carmelo, Toulmé, Jean Jacques, Laguerre, Michel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC165981/
https://ncbi.nlm.nih.gov/pubmed/12853646
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