LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1

Eitemau Tebyg

• NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer
  gan: Lebars, Isabelle, et al.
  Cyhoeddwyd: (2007)
• Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription
  gan: Darfeuille, Fabien, et al.
  Cyhoeddwyd: (2002)
• Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR–TAR* and TAR–aptamer
  gan: Beaurain, François, et al.
  Cyhoeddwyd: (2003)
• Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex
  gan: Van Melckebeke, Hélène, et al.
  Cyhoeddwyd: (2008)
• In vitro selection identifies key determinants for loop-loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1.
  gan: Ducongé, F, et al.
  Cyhoeddwyd: (1999)